{"id":486,"date":"2025-04-17T13:55:56","date_gmt":"2025-04-17T13:55:56","guid":{"rendered":"https:\/\/renewalhow.com\/europe\/premenstrual-disorders-and-premature-menopause\/"},"modified":"2026-06-25T23:07:10","modified_gmt":"2026-06-25T23:07:10","slug":"premenstrual-disorders-and-premature-menopause","status":"publish","type":"post","link":"https:\/\/renewalhow.com\/europe\/providers\/providers-blog\/premenstrual-disorders-and-premature-menopause\/","title":{"rendered":"Premenstrual disorders and premature menopause"},"content":{"rendered":"

Most women enter menopause between the ages of 45 and 55, according to the World Health Organization (WHO). However, a new study published in JAMA Network Open highlights that women suffering from premenstrual disorders (PMDs) have a higher risk of developing early menopause \u2014 with significant consequences for cardiovascular, bone, and neurological health.<\/p>\n

PMD and Early Menopause: Study Reveals Association with Women’s Health Risks<\/strong><\/h2>\n

Most women enter menopause between the ages of 45 and 55, according to the World Health Organization (WHO)<\/strong>. However, a new study published in JAMA Network Open<\/em> highlights that women suffering from premenstrual disorders (PMDs)<\/strong> have a higher risk of developing early menopause<\/strong> \u2014 with important consequences for cardiovascular, bone, and neurological health.<\/p>\n

PMD and Early Menopause: What is the Relationship?<\/strong><\/h3>\n

Women who reported PMD symptoms were more than twice as likely to enter menopause before the age of 45, compared to those who did not present those symptoms.<\/p>\n

The types of PMD analyzed include:<\/p>\n

    \n
  • Premenstrual Syndrome (PMS)<\/strong>: considered mild, it affects up to 30% of women with symptoms such as irritability and bloating.<\/li>\n
  • Premenstrual Dysphoric Disorder (PMDD)<\/strong>: more severe, it impacts quality of life with psychological, gastrointestinal, dermatological, and neurological symptoms.<\/li>\n<\/ul>\n

    Long-Term Impacts<\/strong><\/h3>\n

    Previous studies have already shown that PMDs are associated with more intense symptoms in postmenopause, such as:<\/p>\n

      \n
    • Hot flashes<\/li>\n
    • Night sweats<\/li>\n
    • Increased risk of hypertension<\/strong>
      <\/strong><\/li>\n
    • Heart diseases<\/strong> and diabetes<\/strong>
      <\/strong><\/li>\n<\/ul>\n

      Additionally, early menopause<\/strong> is linked to worse health of the heart, brain, and bones, increasing the risk of osteoporosis<\/strong> and neuropsychiatric disorders<\/strong>.<\/p>\n

      Aggressive Risk Factors<\/strong><\/h3>\n
        \n
      • Smoking<\/strong>: smoking and former smoking women showed a higher prevalence of early menopause.<\/li>\n
      • Altered hormonal response<\/strong>: women with PMDD had lower levels of nocturnal cortisol, indicating possible dysfunction of the hypothalamic-pituitary axis.<\/li>\n
      • Chronic inflammation<\/strong>: high levels of inflammatory cytokines<\/strong> can accelerate follicular depletion and anticipate menopause.<\/li>\n<\/ul>\n

        Conclusion: Monitoring and Support Are Essential<\/strong><\/h3>\n

        The study reinforces the need for clinical monitoring of women with PMD<\/strong>, especially in more severe cases like PMDD. This attention can help prevent future complications during the transition to menopause.<\/p>\n

        Reference:<\/strong><\/p>\n

        Yang Y, Valdimarsd\u00f3ttir UA, Manson JE, et al. Premenstrual Disorders, Menopause Timing, and Severity of Vasomotor Symptoms. JAMA Netw Open.<\/em> 2023;6(9):e2334545. doi:10.1001\/jamanetworkopen.2023.34545<\/p><\/p>\n","protected":false},"excerpt":{"rendered":"

        Most women enter menopause between the ages of 45 and 55, according to the World Health Organization (WHO). However, a new study published in JAMA Network Open highlights that women who suffer from premenstrual disorders (PMDs) have a higher risk of developing early menopause \u2014 with significant implications for cardiovascular, bone, and neurological health.<\/p>\n","protected":false},"author":0,"featured_media":527,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_rwl_seo_title":"","_rwl_seo_description":"","_rwl_seo_noindex":"","footnotes":""},"categories":[23,21],"tags":[],"class_list":["post-486","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-clinical-practice","category-providers-blog"],"_links":{"self":[{"href":"https:\/\/renewalhow.com\/europe\/wp-json\/wp\/v2\/posts\/486","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/renewalhow.com\/europe\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/renewalhow.com\/europe\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/renewalhow.com\/europe\/wp-json\/wp\/v2\/comments?post=486"}],"version-history":[{"count":1,"href":"https:\/\/renewalhow.com\/europe\/wp-json\/wp\/v2\/posts\/486\/revisions"}],"predecessor-version":[{"id":526,"href":"https:\/\/renewalhow.com\/europe\/wp-json\/wp\/v2\/posts\/486\/revisions\/526"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/renewalhow.com\/europe\/wp-json\/wp\/v2\/media\/527"}],"wp:attachment":[{"href":"https:\/\/renewalhow.com\/europe\/wp-json\/wp\/v2\/media?parent=486"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/renewalhow.com\/europe\/wp-json\/wp\/v2\/categories?post=486"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/renewalhow.com\/europe\/wp-json\/wp\/v2\/tags?post=486"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}